tern.mmrm: Tables and Graphs for Mixed Models for Repeated Measures (MMRM)

Mixed models for repeated measures (MMRM) are a popular choice for analyzing longitudinal continuous outcomes in randomized clinical trials and beyond; see for example Cnaan, Laird and Slasor (1997) <doi:10.1002/(SICI)1097-0258(19971030)16:20%3C2349::AID-SIM667%3E3.0.CO;2-E>. This package provides an interface for fitting MMRM within the 'tern' <https://cran.r-project.org/package=tern> framework by Zhu et al. (2023) and tabulate results easily using 'rtables' <https://cran.r-project.org/package=rtables> by Becker et al. (2023). It builds on 'mmrm' <https://cran.r-project.org/package=mmrm> by Sabanés Bové et al. (2023) for the actual MMRM computations.

Version: 0.3.2
Depends: R (≥ 3.6), tern (≥ 0.9.5)
Imports: checkmate (≥ 2.1.0), cowplot, dplyr (≥ 1.1.0), emmeans (≥ 1.10.4), formatters (≥ 0.5.9), generics, ggplot2, lifecycle (≥ 0.2.0), magrittr, mmrm (≥ 0.3.5), parallelly (≥ 1.25.0), rlang (≥ 1.0.1), rtables (≥ 0.6.10), stats, tidyr (≥ 0.8.3)
Suggests: broom (≥ 0.7.10), grid, knitr (≥ 1.42), maditr (≥ 0.8.1), Matrix, rmarkdown (≥ 2.23), testthat (≥ 3.1), vdiffr (≥ 1.0.7), withr (≥ 2.0.0)
Published: 2024-09-23
DOI: 10.32614/CRAN.package.tern.mmrm
Author: Daniel Sabanés Bové [aut], Joe Zhu [aut, cre], Godwin Yung [aut], Francois Collin [aut], Julia Dedic [aut], Jana Stoilova [aut], F. Hoffmann-La Roche AG [cph, fnd]
Maintainer: Joe Zhu <joe.zhu at roche.com>
BugReports: https://github.com/insightsengineering/tern.mmrm/issues
License: Apache License 2.0
URL: https://github.com/insightsengineering/tern.mmrm, https://insightsengineering.github.io/tern.mmrm/
NeedsCompilation: no
Language: en-US
Materials: NEWS
CRAN checks: tern.mmrm results

Documentation:

Reference manual: tern.mmrm.pdf
Vignettes: Introduction to tern.mmrm (source, R code)

Downloads:

Package source: tern.mmrm_0.3.2.tar.gz
Windows binaries: r-devel: tern.mmrm_0.3.2.zip, r-release: tern.mmrm_0.3.2.zip, r-oldrel: tern.mmrm_0.3.2.zip
macOS binaries: r-release (arm64): tern.mmrm_0.3.2.tgz, r-oldrel (arm64): tern.mmrm_0.3.2.tgz, r-release (x86_64): tern.mmrm_0.3.2.tgz, r-oldrel (x86_64): tern.mmrm_0.3.2.tgz
Old sources: tern.mmrm archive

Reverse dependencies:

Reverse imports: teal.modules.clinical

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